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`Bone Tumors: Important Points ?`
*Site of Origin Mnemonic:*
`"GO OO FEMOR"`
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- *G*: Giant Cell Tumor → *Epiphysis*
- *OO*: Osteosarcoma, Osteochondroma → *Metaphysis*
- *FEMOR*: Fibrosarcoma, Ewing Sarcoma, Myeloma/Metastasis, Osteoid Osteoma, Reticulum Cell Tumor → *Diaphysis*
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*Tumors by Site of Origin:*
- *Epiphyseal Tumors*:
- Giant Cell Tumor (GCT)
- Osteoblastoma
- *Metaphyseal Tumors*:
- Osteosarcoma
- Osteochondroma (Exostosis)
- *Diaphyseal Tumors*:
- Fibrosarcoma
- Ewing Sarcoma
- Multiple Myeloma / Metastasis
- Osteoid Osteoma
- Reticulum Cell Tumor / Round Cell Tumor
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*Important Tumors at a Glance*
1. *Giant Cell Tumor ?*
- 50% occur around the knee
- Locally aggressive
- *"Soap bubble"* appearance on X-ray
- Histology: Multinucleated giant cells
- Age group: 20–40 years
2. *Osteochondroma (Exostosis)*
- Most common benign bone tumor
- Occurs in males <25 years
3. *Osteosarcoma*
- 2nd most common primary malignant bone tumor
- Hematogenous spread → LLB: Lung, Liver, Brain
- X-ray: Codman’s triangle / Sunburst pattern
- Usually arises in metaphysis
4. *Ewing Sarcoma*
- Highly malignant "blue cell" tumor
- Early and aggressive metastasis
- X-ray: Onion-skin periosteal reaction
- Associated with t(11;22) translocation
- Arises in diaphysis
5. *Multiple Myeloma*
- Most common primary malignant bone tumor
- Originates from plasma cells
- Common in older adults
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*Mnemonic: GEOMEDia*
- *G*: Giant Cell → *Epiphysis*
- *O*: Osteosarcoma → *Metaphysis*
- *O*: Osteochondroma → *Metaphysis*
- *E*: Ewing Sarcoma → *Diaphysis*
[6/7, 1:24 AM] null: Answer: D.
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