Biochemistry Past Paper MCQs | Batch 48 First Online Test 1st Year | mosaicbro.com
Biochemistry Past Paper MCQs | Batch 48 First Online Test 1st Year
This is series of Past Paper MCQs series of Biochemistry.
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1
In Crigler-Najjar syndrome, there is?
Correct Answer:D
Explanation:
Crigler-Najjar syndrome is caused by a deficiency of UDP-glucuronyltransferase, leading to impaired bilirubin conjugation. This results in unconjugated hyperbilirubinemia, as unconjugated bilirubin cannot be excreted into bile. The condition is classified into Type I (complete enzyme deficiency) and Type II (partial deficiency).
2
Which of the following is an alpha lactone?
Correct Answer:B
Explanation:
Vitamin D can form an alpha lactone structure due to its secosteroid backbone. Alpha lactones are cyclic esters, and Vitamin D's molecular configuration allows this formation under specific conditions, unlike the other vitamins listed.
3
Eukaryotic DNA is associated with histones (Basic protein) in how much ratio to form nucleosomes?
Correct Answer:A
Explanation:
Nucleosomes consist of a histone octamer (two each of H2A, H2B, H3, and H4) wrapped by 146 base pairs of DNA in a 1:1 ratio. This structure compacts DNA and regulates gene expression by controlling access to genetic material.
4
If a solution is to be a buffer, its pH should be?
Correct Answer:D
Explanation:
Buffers work best when pH equals pKa because the concentrations of the weak acid and its conjugate base are equal. This maximizes the buffer's capacity to resist pH changes upon addition of acids or bases.
5
The only carbohydrate which is not having any chiral carbon atom is?
Correct Answer:A
Explanation:
Dihydroxyacetone lacks a chiral carbon because its central carbon is bonded to two identical groups (two hydroxyls and two hydrogens). This makes it optically inactive, unlike other sugars with asymmetric centers.
6
Fat storing cells of vertebrates are called?
Correct Answer:D
Explanation:
Adipocytes specialize in storing triglycerides. They regulate energy balance, insulation, and endocrine functions by secreting hormones like leptin.
7
In jaundice there is an unconjugated hyperbilirubinemia which is most likely due to?
Correct Answer:D
Explanation:
Unconjugated hyperbilirubinemia arises from excessive hemolysis (e.g., sickle cell anemia), overwhelming the liver's capacity to conjugate bilirubin. This leads to elevated indirect bilirubin levels.