Biochemistry Past Paper MCQs | Batch 48 First Online Test 1st Year | mosaicbro.com
Biochemistry Past Paper MCQs | Batch 48 First Online Test 1st Year
This is series of Past Paper MCQs series of Biochemistry.
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8
Which of the following would NOT benefit a patient with beta-thalassemia major?
Correct Answer:B
Explanation:
Beta-thalassemia major involves a beta-globin chain deficit, causing alpha-globin chain excess. Increasing alpha-globin would worsen the imbalance, leading to more severe anemia and ineffective erythropoiesis.
9
The pH of pure water is neutral the best explanations for this is?
Correct Answer:D
Explanation:
Pure water autoionizes to produce equal concentrations of H+ and OH- ions (10^-7 M each at 25°C), making it neutral (pH 7). This equilibrium defines neutrality, not the absence of ions.
10
Normochromatic normocytic, hypochromic microcytic and hyperchromic macrocytic anemia may be caused by which of the following vitamin?
Correct Answer:D
Explanation:
Vitamin B12 deficiency causes macrocytic anemia due to impaired DNA synthesis in erythroblasts. It also leads to hyperchromic cells, while microcytic anemia is typically linked to iron deficiency (unrelated to B12).
11
Substrates required for hemoglobin biosynthesis are?
Correct Answer:C
Explanation:
Heme synthesis starts with glycine and succinyl-CoA (active succinate) condensing to form δ-aminolevulinic acid (ALA) in the mitochondria. This is the rate-limiting step catalyzed by ALA synthase.
12
Which of the following vitamin has the highest recommended dietary allowance (RDA)?
Correct Answer:C
Explanation:
Vitamin C has the highest RDA (75–90 mg/day for adults) due to its roles in collagen synthesis, antioxidant defense, and immune function. Other vitamins like B6 or folate have lower RDAs (1.3–1.7 mg and 400 µg, respectively).
13
The glycosidic linkage between two glucose molecules in maltose is?
Correct Answer:A
Explanation:
Maltose consists of two glucose units linked by an α(1→4) glycosidic bond. This bond is cleaved by maltase during digestion, releasing free glucose for absorption.
14
Sickle cell anemia is?
Correct Answer:C
Explanation:
Sickle cell anemia results from a specific point mutation (Glu6Val) in the β-globin gene (HBB). This autosomal recessive condition causes hemoglobin polymerization under low oxygen, leading to sickle-shaped RBCs and vaso-occlusive crises.